Naeem Ahmed, 25, and Hassan Raza, 23, both of Westminster Gardens, denied a string of sex offences at Snaresbrook Crown Court
Ahmed denies six counts of rape, one count of controlling a child prostitute, one count of inciting child prostitution and one count of paying for the sexual services of a child.
Raza denies a single count of sexual assault.
Anas Iqbal, 25, of Newham Way, East Ham and Nabil Ahmed, 24, of Chadwell Heath Lane, Romford, also denied charges.
The trial, listed for June 3, is expected to take between four and eight weeks.